Included on Backstage’s list of up-and-coming comedians, Amy Schumer, 31, has proved us right in the last few months. She killed it at Comedy Central’s roast of Roseanne (earning praise from none other than Roseanne) and then a few weeks later with her first special, “Mostly Sex Stuff.” With an upcoming Comedy Central show, Schumer looks poised to be the next Chelsea Handler. (Photo Courtesy Focus Features)