The Dimension movie is a reboot of sorts for the moneymaking franchise, which initially starred Alexa Vega and Daryl Sabara as the kids of superspy parents (Antonio Banderas and Carla Gugino). Rodriguez wrote and directed each installment.
Vega and Sabara are no longer kids -- Vega is nearly 23 and recently engaged -- but Rodriguez wanted to continue the series.
The new movie centers on Alba as a retired spy who has been reactivated. The actress, mother of a toddler in real life, will be playing the mother of a baby and two preteen stepchildren.
The actors cast in the preteen roles will be the new Spy Kids.
Other roles seeking to be filled include Alba's husband, a slightly nerdy investigative reporter (might I suggest Borys Kit?), and the villain, known as the Time Keeper, whose goal it is to stop time.
It is expected that Banderas, Vega and Sabara will return in supporting roles.
Like most of Rodriguez's movies, "Kids" will shoot in Austin. The movie, with a budget of less than $30 million, is eyeing a start next month.
The picture, which also has been known as "Spy Kids 4: Armageddon," will be in 3D.
The new "Kids" marks the third time Alba has worked with Rodriguez. The WME-repped actress starred in 2005's "Sin City" and appears in "Machete," Rodriguez's low-budget grindhouse flick that opens Sept. 3.